Liver transplantation is a surgical procedure replacing a diseased liver with a healthy one from a deceased or living donor. It’s a complex operation for patients with end-stage liver disease, including cirrhosis, hepatitis, and liver cancer. The procedure involves removing the diseased liver and connecting the new liver to blood vessels and bile ducts. Post-transplant, patients require lifelong immunosuppressants to prevent organ rejection and face potential complications like infection, rejection, and bleeding. Success rates vary but have improved significantly, offering a life-extending and life-improving option for many.